Vitamin B5 - Pantothenic Acid Deficiency

Vitamin B5, also called pantothenic acid, belongs to the group of water-soluble B vitamins. Its name originates from the Greek word "pantos", meaning everywhere, as it can be found throughout all living cells.

An adequate supply of pantothenic acid is important as it is incorporated into coenzyme A (CoA), a key player in all aspects of metabolism. Functions of CoA are

• break down fats, carbohydrates, and proteins for energy generation

• produce cholesterol and bile salts

• synthesize cell membranes

• form red blood cells, as well as sex and stress-related hormones

• normal energy-yielding metabolism

• normal mental performance

• normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters

• the reduction of tiredness and fatigue

Conditions / Diseases risk

Wound healing : Studies, primarily in cell models and animals, suggest that vitamin B5 supplements may speed up wound healing, especially following surgery. However, effects in humans regarding wound repair are inconsistent.

High cholesterol and triglycerides : Several small human studies suggest that pantethine, a derivative of vitamin B5, may help to reduce cholesterol and triglycerides in the blood of people with elevated blood lipids.

Inflammatory conditions / diseases : Some pilot studies in humans suggests that pantothenic acid supplements might help to reduce symptoms of inflammatory conditions such as diabetic ulceration, rheumatoid arthritis and acne.

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